Sunday, July 20, 2008

Your querries -Our answers-treating HIV 2

Dear Friends,
I am posting one comment with one example,just to initiate a forum for quenching the thirst of knowledge.

How do we manage HIV-2 patient

I came across a patient from a neighbouring city of Jalandhar,where a young strongly built and nourished man is having HIV2 for many years(4-5) now.
He has been visiting various medical and specilist who see some HIV patients from timew to time. He has carried out viral load test and cd4 n number of times and has varying results ranging from few hundred to thousand Viral copies and 400 to 700 Cd4.
The doctors started treating him because of fall in cd4 with combination of drugs(NRTI and NNRTI's).
The catch here is that no lab detects or does a viral load of HIV 2;the catch is cd4 cna vary in variuos conditions (if you have fever;if you are in bad mood etc) or even has diurnal variations;the catch is Efaviranez and Nevirapine are not at all effective for HIV2.
Lessons-----
if at all one wants to monitor and treat HIV 2-there are no clear guidelines but clinical parameters are the best and to treat please do not use NNRTI,use PI plus nuke backbone.
Open for discussion.
Bharti